Neuroimaging: current role in detecting pre-motor Parkinson's disease.
Identifieur interne : 000C99 ( Main/Exploration ); précédent : 000C98; suivant : 000D00Neuroimaging: current role in detecting pre-motor Parkinson's disease.
Auteurs : Jana Godau [Allemagne] ; Anna Hussl ; Praween Lolekha ; A Jon Stoessl ; Klaus SeppiSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2012.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Parkinson Disease.
- instrumentation : Neuroimaging.
- metabolism : Brain, Motor Neurons, Parkinson Disease.
- methods : Neuroimaging.
- pathology : Brain, Motor Neurons, Parkinson Disease.
- physiopathology : Brain.
- Early Diagnosis, Humans.
Abstract
Convergent evidence suggests a pre-motor period in Parkinson's disease (PD) during which typical motor symptoms have not yet developed although dopaminergic neurons in the substantia nigra have started to degenerate. Advances in different neuroimaging techniques have allowed the detection of functional and structural changes in early PD. This review summarizes the state of the art knowledge concerning structural neuroimaging techniques including magnetic resonance imaging (MRI) and transcranial B-mode-Doppler-sonography (TCS) as well as functional neuroimaging techniques using radiotracer imaging (RTI) with different radioligands in detecting pre-motor PD.
DOI: 10.1002/mds.24976
PubMed: 22508281
Affiliations:
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Le document en format XML
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type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Hussl, Anna" sort="Hussl, Anna" uniqKey="Hussl A" first="Anna" last="Hussl">Anna Hussl</name></author><author><name sortKey="Lolekha, Praween" sort="Lolekha, Praween" uniqKey="Lolekha P" first="Praween" last="Lolekha">Praween Lolekha</name></author><author><name sortKey="Stoessl, A Jon" sort="Stoessl, A Jon" uniqKey="Stoessl A" first="A Jon" last="Stoessl">A Jon Stoessl</name></author><author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="doi">10.1002/mds.24976</idno><idno type="RBID">pubmed:22508281</idno><idno type="pmid">22508281</idno><idno type="wicri:Area/PubMed/Corpus">000E06</idno><idno type="wicri:Area/PubMed/Curation">000E06</idno><idno type="wicri:Area/PubMed/Checkpoint">000D26</idno><idno 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Center of Neurodegenerative Diseases (DZNE), University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Hussl, Anna" sort="Hussl, Anna" uniqKey="Hussl A" first="Anna" last="Hussl">Anna Hussl</name></author><author><name sortKey="Lolekha, Praween" sort="Lolekha, Praween" uniqKey="Lolekha P" first="Praween" last="Lolekha">Praween Lolekha</name></author><author><name sortKey="Stoessl, A Jon" sort="Stoessl, A Jon" uniqKey="Stoessl A" first="A Jon" last="Stoessl">A Jon Stoessl</name></author><author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Brain (metabolism)</term><term>Brain (pathology)</term><term>Brain (physiopathology)</term><term>Early Diagnosis</term><term>Humans</term><term>Motor Neurons (metabolism)</term><term>Motor Neurons (pathology)</term><term>Neuroimaging (instrumentation)</term><term>Neuroimaging (methods)</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson Disease (metabolism)</term><term>Parkinson Disease (pathology)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Neuroimaging</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Brain</term><term>Motor Neurons</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Neuroimaging</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term><term>Motor Neurons</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Early Diagnosis</term><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Convergent evidence suggests a pre-motor period in Parkinson's disease (PD) during which typical motor symptoms have not yet developed although dopaminergic neurons in the substantia nigra have started to degenerate. Advances in different neuroimaging techniques have allowed the detection of functional and structural changes in early PD. This review summarizes the state of the art knowledge concerning structural neuroimaging techniques including magnetic resonance imaging (MRI) and transcranial B-mode-Doppler-sonography (TCS) as well as functional neuroimaging techniques using radiotracer imaging (RTI) with different radioligands in detecting pre-motor PD.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Bade-Wurtemberg</li><li>District de Tübingen</li></region><settlement><li>Tübingen</li></settlement></list><tree><noCountry><name sortKey="Hussl, Anna" sort="Hussl, Anna" uniqKey="Hussl A" first="Anna" last="Hussl">Anna Hussl</name><name sortKey="Lolekha, Praween" sort="Lolekha, Praween" uniqKey="Lolekha P" first="Praween" last="Lolekha">Praween Lolekha</name><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name><name sortKey="Stoessl, A Jon" sort="Stoessl, A Jon" uniqKey="Stoessl A" first="A Jon" last="Stoessl">A Jon Stoessl</name></noCountry><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Godau, Jana" sort="Godau, Jana" uniqKey="Godau J" first="Jana" last="Godau">Jana Godau</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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